ChloroquineV1, France, Analysis, bibRecord, 000248

Antiplasmodial benzophenone derivatives from the root barks of Symphonia globulifera (Clusiaceae).

Identifieur interne : 000248 ( France/Analysis ); précédent : 000247; suivant : 000249

Antiplasmodial benzophenone derivatives from the root barks of Symphonia globulifera (Clusiaceae).

Auteurs : Guillaume Marti [France] ; Véronique Eparvier [France] ; Christian Moretti ; Soizic Prado ; Philippe Grellier ; Nathalie Hue ; Odile Thoison [France] ; Bernard Delpech [France] ; Françoise Guéritte [France] ; Marc Litaudon [France]

Source :

Phytochemistry [ 0031-9422 ] ; 2010-06.

RBID : Hal:hal-00491751

Abstract

In an effort to find antimalarial drugs, a systematic in vitro evaluation on a chloroquine-resistant strain of Plasmodium falciparum (FcB1) was undertaken on sixty plant extracts collected in French Guiana. The ethyl acetate extract obtained from the root barks of Symphonia globulifera exhibited a strong antiplasmodial activity (97% at 10 microg/ml). The phytochemical investigation of this extract led to the isolation of nine polycyclic polyprenylated acylphloroglucinol (PPAPs) compounds and two oxidized derivatives. All compounds showed antiplasmodial activity with IC(50)s ranged from 2.1 to 10.1 microM. A LC/ESI-MS(n) study performed on polyprenylated benzophenones previously isolated from Moronobea coccinea provided a reliable method for their detection in the extract and structural elucidation.

Url:

https://hal.archives-ouvertes.fr/hal-00491751

DOI: 10.1016/j.phytochem.2010.03.008

Affiliations:

France

Links toward previous steps (curation, corpus...)

to stream Hal, to step Corpus: 000025
to stream Hal, to step Curation: 000025
to stream Hal, to step Checkpoint: 000181
to stream Main, to step Merge: 001608
to stream Main, to step Curation: 001606
to stream Main, to step Exploration: 001606
to stream France, to step Extraction: 000248

Links to Exploration step

Hal:hal-00491751

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antiplasmodial benzophenone derivatives from the root barks of Symphonia globulifera (Clusiaceae).</title>
<author><name sortKey="Marti, Guillaume" sort="Marti, Guillaume" uniqKey="Marti G" first="Guillaume" last="Marti">Guillaume Marti</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Eparvier, Veronique" sort="Eparvier, Veronique" uniqKey="Eparvier V" first="Véronique" last="Eparvier">Véronique Eparvier</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Moretti, Christian" sort="Moretti, Christian" uniqKey="Moretti C" first="Christian" last="Moretti">Christian Moretti</name>
</author>
<author><name sortKey="Prado, Soizic" sort="Prado, Soizic" uniqKey="Prado S" first="Soizic" last="Prado">Soizic Prado</name>
</author>
<author><name sortKey="Grellier, Philippe" sort="Grellier, Philippe" uniqKey="Grellier P" first="Philippe" last="Grellier">Philippe Grellier</name>
</author>
<author><name sortKey="Hue, Nathalie" sort="Hue, Nathalie" uniqKey="Hue N" first="Nathalie" last="Hue">Nathalie Hue</name>
</author>
<author><name sortKey="Thoison, Odile" sort="Thoison, Odile" uniqKey="Thoison O" first="Odile" last="Thoison">Odile Thoison</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Delpech, Bernard" sort="Delpech, Bernard" uniqKey="Delpech B" first="Bernard" last="Delpech">Bernard Delpech</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Gueritte, Francoise" sort="Gueritte, Francoise" uniqKey="Gueritte F" first="Françoise" last="Guéritte">Françoise Guéritte</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Litaudon, Marc" sort="Litaudon, Marc" uniqKey="Litaudon M" first="Marc" last="Litaudon">Marc Litaudon</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:hal-00491751</idno>
<idno type="halId">hal-00491751</idno>
<idno type="halUri">https://hal.archives-ouvertes.fr/hal-00491751</idno>
<idno type="url">https://hal.archives-ouvertes.fr/hal-00491751</idno>
<idno type="doi">10.1016/j.phytochem.2010.03.008</idno>
<date when="2010-06">2010-06</date>
<idno type="wicri:Area/Hal/Corpus">000025</idno>
<idno type="wicri:Area/Hal/Curation">000025</idno>
<idno type="wicri:Area/Hal/Checkpoint">000181</idno>
<idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000181</idno>
<idno type="wicri:doubleKey">0031-9422:2010:Marti G:antiplasmodial:benzophenone:derivatives</idno>
<idno type="wicri:Area/Main/Merge">001608</idno>
<idno type="wicri:Area/Main/Curation">001606</idno>
<idno type="wicri:Area/Main/Exploration">001606</idno>
<idno type="wicri:Area/France/Extraction">000248</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Antiplasmodial benzophenone derivatives from the root barks of Symphonia globulifera (Clusiaceae).</title>
<author><name sortKey="Marti, Guillaume" sort="Marti, Guillaume" uniqKey="Marti G" first="Guillaume" last="Marti">Guillaume Marti</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Eparvier, Veronique" sort="Eparvier, Veronique" uniqKey="Eparvier V" first="Véronique" last="Eparvier">Véronique Eparvier</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Moretti, Christian" sort="Moretti, Christian" uniqKey="Moretti C" first="Christian" last="Moretti">Christian Moretti</name>
</author>
<author><name sortKey="Prado, Soizic" sort="Prado, Soizic" uniqKey="Prado S" first="Soizic" last="Prado">Soizic Prado</name>
</author>
<author><name sortKey="Grellier, Philippe" sort="Grellier, Philippe" uniqKey="Grellier P" first="Philippe" last="Grellier">Philippe Grellier</name>
</author>
<author><name sortKey="Hue, Nathalie" sort="Hue, Nathalie" uniqKey="Hue N" first="Nathalie" last="Hue">Nathalie Hue</name>
</author>
<author><name sortKey="Thoison, Odile" sort="Thoison, Odile" uniqKey="Thoison O" first="Odile" last="Thoison">Odile Thoison</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Delpech, Bernard" sort="Delpech, Bernard" uniqKey="Delpech B" first="Bernard" last="Delpech">Bernard Delpech</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Gueritte, Francoise" sort="Gueritte, Francoise" uniqKey="Gueritte F" first="Françoise" last="Guéritte">Françoise Guéritte</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Litaudon, Marc" sort="Litaudon, Marc" uniqKey="Litaudon M" first="Marc" last="Litaudon">Marc Litaudon</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-440" status="VALID">          <orgName>Institut de Chimie des Substances Naturelles</orgName>
          <orgName type="acronym">ICSN</orgName>
          <desc>            <address>              <addrLine>Avenue de la terrasse 91198 Gif sur yvette cedex</addrLine>
              <country key="FR"></country>
            </address>
          </desc>
          <listRelation>            <relation name="UPR2301" active="#struct-441569" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle name="UPR2301" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID">          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
            <ref type="url">http://www.cnrs.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
</analytic>
<idno type="DOI">10.1016/j.phytochem.2010.03.008</idno>
<series><title level="j">Phytochemistry</title>
<idno type="ISSN">0031-9422</idno>
<imprint><date type="datePub">2010-06</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">              <p>In an effort to find antimalarial drugs, a systematic in vitro evaluation on a chloroquine-resistant strain of Plasmodium falciparum (FcB1) was undertaken on sixty plant extracts collected in French Guiana. The ethyl acetate extract obtained from the root barks of Symphonia globulifera exhibited a strong antiplasmodial activity (97% at 10 microg/ml). The phytochemical investigation of this extract led to the isolation of nine polycyclic polyprenylated acylphloroglucinol (PPAPs) compounds and two oxidized derivatives. All compounds showed antiplasmodial activity with IC(50)s ranged from 2.1 to 10.1 microM. A LC/ESI-MS(n) study performed on polyprenylated benzophenones previously isolated from Moronobea coccinea provided a reliable method for their detection in the extract and structural elucidation.</p>
            </div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
</country>
</list>
<tree><noCountry><name sortKey="Grellier, Philippe" sort="Grellier, Philippe" uniqKey="Grellier P" first="Philippe" last="Grellier">Philippe Grellier</name>
<name sortKey="Hue, Nathalie" sort="Hue, Nathalie" uniqKey="Hue N" first="Nathalie" last="Hue">Nathalie Hue</name>
<name sortKey="Moretti, Christian" sort="Moretti, Christian" uniqKey="Moretti C" first="Christian" last="Moretti">Christian Moretti</name>
<name sortKey="Prado, Soizic" sort="Prado, Soizic" uniqKey="Prado S" first="Soizic" last="Prado">Soizic Prado</name>
</noCountry>
<country name="France"><noRegion><name sortKey="Marti, Guillaume" sort="Marti, Guillaume" uniqKey="Marti G" first="Guillaume" last="Marti">Guillaume Marti</name>
</noRegion>
<name sortKey="Delpech, Bernard" sort="Delpech, Bernard" uniqKey="Delpech B" first="Bernard" last="Delpech">Bernard Delpech</name>
<name sortKey="Eparvier, Veronique" sort="Eparvier, Veronique" uniqKey="Eparvier V" first="Véronique" last="Eparvier">Véronique Eparvier</name>
<name sortKey="Gueritte, Francoise" sort="Gueritte, Francoise" uniqKey="Gueritte F" first="Françoise" last="Guéritte">Françoise Guéritte</name>
<name sortKey="Litaudon, Marc" sort="Litaudon, Marc" uniqKey="Litaudon M" first="Marc" last="Litaudon">Marc Litaudon</name>
<name sortKey="Thoison, Odile" sort="Thoison, Odile" uniqKey="Thoison O" first="Odile" last="Thoison">Odile Thoison</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/France/Analysis

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000248 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000248 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    France
   |étape=   Analysis
   |type=    RBID
   |clé=     Hal:hal-00491751
   |texte=   Antiplasmodial benzophenone derivatives from the root barks of Symphonia globulifera (Clusiaceae).
}}

This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021

	Serveur d'exploration Chloroquine
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Chloroquine

Antiplasmodial benzophenone derivatives from the root barks of Symphonia globulifera (Clusiaceae).

Antiplasmodial benzophenone derivatives from the root barks of Symphonia globulifera (Clusiaceae).

Source :

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri